What should I feed my German Shepherd Dog with EPI (Exocrine Pancreatic Insufficiency)?

Exocrine Pancreatic Insufficiency (EPI) is a condition in which the pancreas fails to produce sufficient digestive enzymes, meaning a dog cannot properly digest and absorb nutrients from their food. It is relatively common in German Shepherd Dogs and can be managed effectively with the right approach.

The cornerstone of EPI management is pancreatic enzyme replacement therapy (PERT). This involves mixing powdered pancreatic enzymes (such as Pancrex V or similar veterinary preparations) into your dog's food before each meal. Without this, even the best-quality food will not be properly absorbed.

In terms of the diet itself, a highly digestible, low-fat food is generally recommended. High fat content can exacerbate digestive issues in EPI dogs. Look for foods with named, easily digestible protein sources (cooked chicken, turkey, or fish) and avoid high-fibre diets, as fibre can interfere with enzyme activity and nutrient absorption.

Some EPI dogs also develop secondary issues such as bacterial overgrowth in the small intestine (SIBO) or vitamin B12 (cobalamin) deficiency, both of which may require additional supplementation. Your vet will be able to monitor for these and advise accordingly.

Feeding little and often — two to three smaller meals per day rather than one large meal — tends to work well for EPI dogs. Raw diets are sometimes advocated by owners, though the evidence is mixed and it's important to discuss any major dietary changes with your vet first.

If your dog has been newly diagnosed with EPI, the most important step is to work closely with your veterinary practice to establish the correct enzyme dose and monitor weight and condition carefully.